POLYMORPHISM OF DNA MARKERS OF Y-CHROMOSOMES OF A SAMPLE REPRESENTATIVES OF THE BELARUSIAN POPULATION

UDC 575.22

  • Mironchik Polina Alekseevna – works foreman. RUРE “Belmedpreparaty” (30, Fabritsiusa str., 220007, Minsk, Republic of Belarus). E-mail: polinamironchik@gmail.com

  • Stasevich Ol’ga Viktorovna – PhD (Chemistry), Associate Professor, Assistant Professor, the Department of Physical-Chemical Methods for Products Certification. Belarusian State Technological University (13a, Sverdlova str., 220006, Minsk, Republic of Belarus). E-mail: stasevich@belstu.by

DOI: https://doi.org/10.52065/2520-2669-2022-253-1-54-57

Key words: DNA-analysis, molecular-genetic identification, biological samples, STR-locuses of Y-chromosome, haplotype, population samples, genotyping.

For citation: Mironchik P. A., Stasevich O. V. Polymorphism of DNA markers of Y-chromosomes of a sample representatives of the Belarusian population. Proceedings of BSTU, issue 2, Chemical Engineering, Biotechnologies, Geoecology, 2022, no. 1 (253), pp. 54–57 (In Russian). DOI: https://doi.org/10.52065/2520-2669-2022-253-1-54-57.

Abstract

Genotyping of 153 samples of biological material (buccal epithelium) of male donors who live at the territory of the Republic of Belarus has been carried out. According to the results of the study, the samples were assigned to a specific haplogroup of the Y-chromosome and their terminal mutations were established. It was shown that the studied sample predominantly contains the R1a haplogroup, followed by the number of samples in the sample were the I2a1b3a, N1a1 and E1b1b haplogroups. At the same time, in haplogroup R1a, mutations Y5570 (14.8%), YP593 (7.4%), YP270 (6.2%) were most often encountered. Thus, the haplogroup R1a is the most numerous in the presented sample of the Belarusian population, which corresponds to the literature data and shows that Belarusians belong to the Eastern European peoples.

Download

References

  1.  Rychkov U. G. Genofond i genogeografiya narodonaseleniya. Genofond naseleniya Rossii i sopredel’nykh stran [Gene pool and genogeography of the population. The gene pool of the population of Russia and neighboring countries]. St. Petersburg, Nauka Publ., 2000. Vol. 1. 611 p. (In Russian).
  2. Altuhov U. P. Geneticheskiye protsessy v populyatsiyakh [Genetic processes in populations]. Moscow, Nauka Publ., 2003. 431 p. (In Russian).
  3. Cybovskiy I. S., Kuzub N. N., Kotova S. A., Veremejchik V. M., Kartel’ N. A. Metodicheskiye rekomendatsii po vydeleniyu DNK iz biologicheskikh sledov pri sudebno-ekspertnoy identifikatsii kriminalisticheskikh ob”yektov [Guidelines for the extraction of DNA from biological traces in the forensic identification of forensic objects]. Minsk, Pravo i ekonomika Publ., 2010. 32 p. (In Russian).
  4. Butler J. M., Schoske R., Vallone P. M., Kline M. C., Redd A. J., Hammer M. F. A novel multiplex for simultaneous amplification of 20 Y chromosome STR markers. Forensic Sci. Int., 2002, vol. 129, pp. 10–24.
  5. Balanovskiy O. P. Izmenchivost’ genofonda v prostranstve i vremeni: sintez dannykh o genogeografii mitokhondrial’noy DNK i Y-khromosomy: avtoreferat dissertatsii doktora biologicheskikh nauk [Variability of the gene pool in space and time: synthesis of data on the genogeography of mitochondrial DNA and the Y-chromosome. Abstract of thesis DSc (Biology)]. Moskow, 2012. 45 p.
15.11.2021